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Frequently Asked Questions - Microbicides

What are microbicides?
Microbicides are substances used in the vagina or rectum to help prevent sexually transmitted diseases (STDs), including HIV. They are not yet available, but scientists are testing them to determine if they are safe and how well they work.

How are microbicides used?
Microbicides are used as a gel, cream or suppository to be put into the vagina or rectum before having sex.

Are microbicides safe?
All new microbicides have to pass strict tests to make sure they are safe before they are made available to people.

How do microbicides work?
Microbicides can work in several different ways, including:

  • They can block viruses or bacteria from infecting the vagina or rectum
  • They can kill or weaken STDs
  • They can strengthen a person's immune system to prevent the infection from taking hold

Describe the microbicide products that are being tested in the HPTN.
Four microbicide products are being tested in the HPTN. They include:

  • PRO 2000 Gel - stops HIV from entering cells
  • Buffer Gel -maintains the normal acidic environment of the vagina, which may kill HIV
  • PMPA -like some drugs used to treat HIV, stops HIV from multiplying in cells
  • Cellulose Sulfate (CS) - stops HIV from entering cells

Will microbicides replace the need for condoms?
No. Condoms offer the best known protection against STDs and HIV when they are used correctly. But many women can't control whether the man uses a condom, and microbicides would offer them some protection.

What if a woman wants to get pregnant?
Research is being done on both microbicides that allow women to get pregnant and microbicides that prevent pregnancy. Women's health groups advocate for both types of products.

      
 

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This page was last updated: June 07, 2007