Study Oversight

Several committees provide oversight and review of HPTN 052.  This website provides information regarding the membership and activities of these committees.

• Clinical Management Committee (CMC)
  • The CMC is responsible for answering clinically-related questions. Questions to this committee can include, but are not limited to:
    • Questions about inclusion and exclusion criteria for particular participants
    • Questions about protocol interpretation
    • Questions about ART management (e.g., regimen change or toxicity management)
    • Questions about primary HIV care
    • Questions about the clinical management of co-morbidities
    • Questions about the prophylaxis and treatment of OIs
    • Questions about AE management
    • Questions about grading and reporting AEs and EAEs
  • Clinically-related questions may be submitted to the CMC by sending email to 052CMC@HPTN.org
  • CMC Roster
  • CMC Schedule (Jul 2011 - Feb 2012) (Effective 31 Jul 2011)
  • CMC Questions and Answers

• Protocol Safety Review Team (PSRT)
  • The PSRT conducts regular reviews of standardized study safety data reports and relays any identified safety concerns to the DAIDS Vaccine and Prevention Data and Safety Monitory Board.