|
NIMH Project Accept/HPTN 043
A Phase III
Randomized Controlled Trial of Community Mobilization, Mobile Testing, Same-Day
Results, and Post-Test Support for HIV in Sub-Saharan Africa and Thailand
What is
NIMH Project Accept/HPTN 043?
NIMH Project Accept is an HIV prevention trial in
which 34 communities in Africa (in South Africa, Tanzania, and Zimbabwe) and 14
communities in Thailand are being randomized to receive either a community-based
HIV voluntary counseling and testing (CBVCT) intervention plus standard
clinic-based VCT (SVCT), or SVCT alone. The CBVCT intervention has three major
strategies: (1) to make VCT more available in community settings; (2) to engage
the community through outreach; and (3) to provide post-test support. These
strategies are designed to change community norms and reduce risk for HIV
infection among all community members, irrespective of whether they participated
directly in the intervention.
A community-level intervention based on modifying
community norms can change the environmental context in which people make
decisions about HIV risk, and has the potential to alter the course of the HIV
epidemic in developing countries. This is the first international randomized
controlled Phase III trial to determine the efficacy of a behavioral/social
science intervention with an HIV incidence endpoint.
NIMH Project Accept is funded as a National
Institute of Mental Health (NIMH) Cooperative Agreement involving the NIMH
and several U.S. and international institutions. The HIV Prevention Trials
Network (HPTN) is also providing support to the project (HPTN 043)); support has
also been provided by the Office of AIDS Research of the National Institutes of
Health.
Visit the
NIMH
Project Accept website to learn more about the study, the sites where it is
being implemented, and the members of the study teams at each site. The
study protocol and other documents are also available on the study website.
Questions about
NIMH Project Accept/HPTN 043 should be directed to:
Greg Szekeres
UCLA David Geffen School of Medicine
Division of Infectious Diseases
10940 Wilshire Boulevard
Suite 1220, Box 957320
Los Angeles, CA 90024-3916
U.S.A.
Phone: 310-794-3579
Fax: 310-794-2795
Email: gszekeres@mednet.ucla.edu
|
