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Study
Status Table
Studies
& Sites Table
Studies
by Country
Studies
by Research Area
Study
Phase Definitions
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HPTN Studies by Research Area
The HPTN conducts studies developed through its
six scientific research working groups.
ART
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HPTN 034 |
HIV Incidence and Participant Retention Protocol, Pune, India |
(Participants Off Study & Primary Analysis Complete) |
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HPTN 052 |
A Randomized Trial to Evaluate the Effectiveness of Antiretroviral Therapy Plus HIV Primary Care versus HIV Primary Care Alone to Prevent the Sexual Transmission of HIV-1 in Serodiscordant Couples |
(Enrolling) |
Behavior
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HIVNET 015 |
EXPLORE: A Randomized Clinical Trial of the Efficacy of a Behavioral Intervention to Prevent Acquisition of HIV among Men who have Sex with Men (MSM) |
(Concluded) |
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HPTN 043 |
A Phase III Randomized Controlled Trial of Community Mobilization, Mobile Testing, Same-Day Results, and Post-Test Support for HIV in Sub-Saharan Africa and Thailand |
(Enrolling) |
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HPTN 061 |
Feasibility of a community-level, multi-component intervention for Black MSM in preparation for a Phase IIB community-level randomized trial to test the efficacy of the intervention in reducing HIV incidence among Black MSM |
(In Development) |
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HPTN 062 |
An Individual-Level Prevention Intervention for Individuals with Acute HIV Infection |
(In Development) |
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HPTN 063 |
Preparing for international prevention trials involving HIV-infected individuals in care settings |
(In Development) |
Microbicide
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HIVNET 016A |
Condom Promotion and Counseling Study |
(Concluded) |
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HPTN 032 |
Male Tolerance Study of BufferGel and PRO 2000/5 Gel (P) |
(Concluded) |
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HPTN 035 |
Phase II/IIb Safety and Effectiveness Study of the Vaginal Microbicides BufferGel and 0.5% PRO2000/5 Gel (P) for the Prevention of HIV Infection in Women |
(Closed to Accrual) |
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HPTN 047 |
A Phase I Safety and Acceptability Study of the Investigational Vaginal Microbicide PRO 2000/5 Gel (P) |
(Concluded) |
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HPTN 049 |
Phase I Safety and Acceptability Study of the Vaginal Microbicide 6% Cellulose Sulfate Gel Among HIV-Infected Women |
(Concluded) |
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HPTN 050 |
Phase I Safety and Acceptability Study of the Vaginal Microbicide Agent PMPA Gel |
(Concluded) |
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HPTN 055 |
HIV Prevention Preparedness Study |
(Concluded) |
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HPTN 056 |
Characterization of Baseline Mucosal Indices of Injury and Inflammation in Men for Use in Rectal Microbicide Trials |
(Participants Off Study & Primary Analysis Complete) |
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HPTN 059 |
Phase II Expanded Safety and Acceptability Study of the Vaginal Microbicide 1% Tenofovir Gel |
(Closed to Follow Up) |
Perinatal
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HIVNET 012 |
A Phase IIB Trial to Determine the Efficacy of Oral AZT and the Efficacy of Oral Nevirapine for the Prevention of Vertical Transmission of HIV-1 Infection in Pregnant Ugandan Women and Their Neonates |
(Closed to Follow Up) |
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HIVNET 024 |
Phase III Trial of Antibiotics to Reduce Chorioamnionitis-Related Perinatal HIV Transmission |
(Participants Off Study & Primary Analysis Complete) |
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HPTN 027 |
A Phase I Study to Evaluate the Safety and Immunogenicity of ALVAC-HIV vCP1521 in Infants Born to HIV-1 Infected Women in Uganda |
(Closed to Accrual) |
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HPTN 046 |
Phase III Trial to Determine the Efficacy and Safety of an Extended Regimen of Nevirapine in Infants Born to HIV Infected Women to Prevent Vertical HIV Transmission During Breastfeeding |
(Enrolling) |
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HPTN 057 |
A Phase I Open Label Trial of the Safety and Pharmacokinetics of Tenofovir Disoproxil Fumarate in HIV-1 Infected Pregnant Women and their Infants |
(Enrolling) |
STDs
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HPTN 036 |
HIV Prevalence, Incidence, and HSV-2 Prevalence Among High-Risk MSM in Perú |
(Concluded) |
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HPTN 039 |
A Phase III, randomized, double-blind, placebo-controlled trial of acyclovir for the reduction of HIV acquisition among high risk HSV-2 seropositive, HIV-seronegative individuals |
(Participants Off Study & Primary Analysis Complete) |
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HPTN 039-01 |
Ancillary Study: Prospective Cohort Study of HPTN 039 Seroconverters: The Effect of HSV-2 Suppression on HIV-1 Viral Set Point |
(Closed to Accrual) |
Substance Use
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HPTN 033 |
HIV Prevention Preparedness Study |
(Closed to Follow Up) |
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HPTN 037 |
A Phase III Randomized Study to Evaluate the Efficacy of a Network-oriented Peer Educator Intervention for the Prevention of HIV Transmission Among Injection Drug Users And Their Network Members |
(Closed to Follow Up) |
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HPTN 058 |
A Phase III randomized controlled trial to evaluate the efficacy of drug treatment in prevention of HIV infection among opiate dependent injectors |
(Enrolling) |
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