The HPTN leadership group is a subset of the Executive Committee (EC). The EC includes investigators from the Clinical Trials Units (CTUs), the Leadership and Operations Center (LOC), the Statistical and Data Management Center (SDMC), the Laboratory Center (LC), Community representatives, National Institutes of Health (NIH) representatives, and other individuals with expertise in HPTN scientific research areas.

The EC, under the direction of the HPTN Principal Investigators (PIs) Wafaa El-Sadr and Myron S. Cohen, in conjunction with NIH, sets the research priorities of the HPTN and directs its scientific agenda.

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