Prospective cohort study
Approximately 800 volunteers aged 18 or older
8 months (includes enrollment) with possible extension in response to evolving information regarding SARS-CoV-2 infection and COVID-19.
Primary objective 1: To generate standardized datasets characterizing the quality, magnitude, and kinetics
of humoral immune responses to SARS-CoV-2 infection in asymptomatic participants and symptomatic participants (both hospitalized and non-hospitalized) experiencing a range of clinical outcomes in order to prepare for similar assessments during trials of immune-based preventive strategies.
Primary objective 2: To characterize innate and cellular immune responses to SARS-CoV-2 infection
during infection with SARS-CoV-2 in asymptomatic and acutely symptomatic participants (both hospitalized and non-hospitalized).