A Phase III Randomized Study to Evaluate the Efficacy of a Network-oriented Peer Educator Intervention for the Prevention of HIV Transmission Among Injection Drug Users And Their Network Members
What was HPTN 037?
A Phase III, multi site, two-arm, randomized controlled trial to determine the efficacy of a network-oriented peer educator intervention for prevention of HIV infection among injection drug users and members of their HIV risk network through reduction of HIV risk behaviors.
Who participated in the study?
Approximately 2,610 HIV uninfected injection drug users (index participants) and individuals identified by each index participant as members of their sex and drug-using networks (network members).
What happened during the study?
Index participants and their network members were randomized to one of two groups in a ratio of 1:1. Index participants and network members in both arms received basic HIV counseling and testing enhanced with interactive risk reduction counseling. In addition, index participants randomized to the experimental arm received peer educator training (see protocol for treatment regimen table).