The MRC ensures that manuscripts containing data or statistically related content from HPTN studies are developed, reviewed, and endorsed for submission. The MRC is responsible for ensuring the timely development of manuscripts by the protocol team. It is responsible for the review (within five days of submission to the MRC) and provides written comments on the manuscript and specific rationale for any revisions requested. Reviews are conducted via conference calls on an as-needed basis upon manuscript submission. Conference calls are organized by the MRC Chair, Deborah Donnell.