Press Releases

August 2018

DURHAM, NC – Investigators from the HIV Prevention Trials Network (HPTN) today announced The Lancet has published key results from HPTN 074.

July 2018

The HIV Prevention Trials Network (HPTN) congratulates the participants and researchers taking part in two important HIV prevention trials announcing results this week at the AIDS 2018 conference – the Sustainable East Africa Research in Community Health (SEARCH) study and the Botswana Combination Prevention Project (BCPP) study. Both studies were cluster-randomized, community-based trials conducted in sub-Saharan Africa that measured the impact of enhanced HIV services and the offer of universal treatment on HIV incidence.

November 2017

DURHAM, N.C. – The HIV Prevention Trials Network (HPTN) today announced the initiation of HPTN 084, a Phase 3 double-blind safety and efficacy study of long-acting injectable cabotegravir (CAB) compared to a combination of daily oral tenofovir disoproxil fumarate 300 mg plus emtricitabine 200 mg (TDF/FTC).

July 2017

DURHAM, N.C. – Study results released today by the HIV Prevention Trials Network (HPTN) show long-acting injectable cabotegravir (CAB LA) to be well tolerated by men and women and support the dosing schedule currently being used in a phase 3 HPTN study for HIV prevention. Analysis of HPTN 077 study data presented today at the 9th IAS Conference on HIV Science in Paris, France, supported further development of CAB LA for HIV prevention in men and women using 600mg (3 mL) injections every eight weeks with the first two injections given four weeks apart.

June 2017

DURHAM, N.C. - The HPTN 065 study, conducted by the HIV Prevention Trials Network (HPTN), showed that financial incentives can motivate some people living with HIV (PLWH) to take their HIV antiretroviral therapy (ART) medication regularly and maintain viral load suppression. This finding could have implications for improving health outcomes and decreasing the risk of transmitting the virus to others. Study findings were published today in JAMA Internal Medicine.

December 2016

DURHAM, N.C. – The HIV Prevention Trials Network (HPTN) has launched a new study, HPTN 083, to evaluate whether injectable cabotegravir (CAB) can safely protect men who have sex with men (MSM) and transgender women (TGW) who have sex with men from acquiring HIV as well as daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC). If found to be safe and effective for HIV pre-exposure prophylaxis, also known as PrEP, injectable CAB may be easier for some people to adhere to than daily oral TDF/FTC.

July 2016

The HIV Prevention Trials Network (HPTN) commends the participants and researchers on successful completion of the ANRS 12249 TasP (Treatment as Prevention) Study.  The study was conducted in a rural area of northern KwaZulu-Natal (South Africa) where HIV incidence was compared between communities randomized to either immediate offer of antiretroviral therapy (ART) for all individuals diagnosed with HIV, or standard of care ART initiation.  Both study arms included home-based HIV testing.  

July 2016

DURBAN, South Africa and DURHAM, N.C. – Investigators from the HIV Prevention Trials Network (HPTN) today announced key results from the HPTN 073 Study at the International AIDS Conference (AIDS 2016) in Durban, South Africa. The study, which assessed uptake and adherence of oral pre-exposure prophylaxis (PrEP) for the prevention of HIV infection among Black men who have sex with men (BMSM) in the U.S., demonstrated consistency between self-report and biological markers of adherence.

July 2016

DURHAM, N.C. – The HIV Prevention Trials Network (HPTN) announced today that the final results of the HPTN 052 study were published in the New England Journal of Medicine (NEJM). This pivotal study demonstrated that antiretroviral therapy (ART) for HIV infection provides durable and reliable protection against the sexual transmission of the virus from infected men and women to their HIV-uninfected sexual partners.

April 2016

First Study to Evaluate Efficacy of Broadly Neutralizing Monoclonal Antibody in Reducing Acquisition of HIV-1 Infection Among At Risk Populations

February 2016

BOSTON and DURHAM, N.C. – Investigators from the HIV Prevention Trials Network (HPTN) today announced key results from the HPTN 073 Study at the 2016 Conference on Retroviruses and Opportunistic Infections (CROI) in Boston, Massachusetts. The study showed high uptake of pre-exposure prophylaxis (PrEP) for prevention of HIV infection among Black men who have sex with men (BMSM) in the U.S. with the use of a novel coordinated counseling and care approach resulting in findings suggestive of a lower rate of HIV infection. 

July 2015

VANCOUVER, B.C. and DURHAM, N.C. - A Phase III, individually randomized trial has found conditional cash transfers for school attendance did not reduce the risk of HIV among high-school aged women in South Africa, investigators from the HIV Prevention Trials Network (HPTN) reported today at the 8th International AIDS Society (IAS) Conference on HIV Pathogenesis, Treatment and Prevention in Vancouver, Canada. The new finding is from HPTN 068, the first individually randomized study of young women conditioned on school attendance with an HIV incidence endpoint.

July 2015

VANCOUVER, B.C. and DURHAM, N.C. - Antiretroviral therapy (ART) for HIV infection provides lasting protection against the sexual transmission of the virus from infected men and women to their HIV-uninfected sexual partners, investigators from the HIV Prevention Trials Network (HPTN) reported today at the 8th International AIDS Society (IAS) Conference on HIV Pathogenesis, Treatment and Prevention in Vancouver, Canada.

July 2015

VANCOUVER, B.C. and DURHAM, N.C. - Results from HPTN 067, a Phase II, randomized, open-label study, demonstrate most study participants had higher coverage of sex events and better adherence when they were assigned to the daily dosing arm, investigators from the HIV Prevention Trials Network (HPTN) reported today at the 8th International AIDS Society (IAS) Conference on HIV Pathogenesis, Treatment and Prevention in Vancouver, Canada.

February 2015

The HIV Prevention Trials Network (HPTN) has launched two new phase 2 studies, HPTN 076 and HPTN 077, which are designed to evaluate new drugs to protect people from getting infected with HIV.

HPTN 076 and HPTN 077 are among the first studies to test long-acting, injectable antiretroviral drugs in persons without HIV infection. Antiretroviral drugs are commonly used now as treatment in individuals with HIV infection.

The studies are funded by the National Institute of Allergy and Infectious Diseases, which is part of the U.S. National Institutes of Health.