About the HPTN

Mission Statement

The HPTN is dedicated to the discovery and development of new and innovative research strategies to reduce the acquisition and transmission of HIV.

The HIV Prevention Trials Network (HPTN) is a worldwide collaborative clinical trials network that brings together investigators, ethicists, community and other partners to develop and test the safety and efficacy of interventions designed to prevent the acquisition and transmission of HIV. HPTN studies evaluate new HIV prevention interventions and strategies in populations and geographical regions that bear a disproportionate burden of infection.

The HPTN research agenda is focused primarily on the use of integrated strategies: use of antiretroviral drugs (antiretroviral therapy and pre-exposure prophylaxis); interventions for substance abuse, particularly injection drug use; behavioral risk reduction interventions and structural interventions. The HPTN is committed to the highest ethical standards for its clinical trials and recognizes the importance of community engagement in all phases of the research process.

The HPTN was established in 2000, building on the work of the HIV Network for Prevention Trials (HIVNET). HPTN’s Leadership and Operations Center (LOC), is based at FHI 360, Durham, NC. Its Laboratory Center (LC) is at Johns Hopkins University, Baltimore, MD and its Statistical and Data Management Center (SDMC) is housed within the Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at the Fred Hutchinson Cancer Research Center in Seattle, Washington.

HPTN receives its funding from three NIH institutes: the National Institute of Allergy and Infectious Diseases, the National Institute of Mental Health and the National Institute on Drug Abuse.


Conversations with the HPTN

Sarah Fidler, MBBS, PhD, FRCP, is currently working in the Department of Medicine at Imperial College London as a clinical academic; she is a Professor and Consultant Physician in HIV Medicine.

Ernest Moseki is a community engagement coordinator at the Gaborone CRS in Gaborone, Botswana. He is currently a member of the HPTN Community Working Group Steering Committee and the HPTN 075 protocol team. Ernest is the first regulatory and administrative coordinator for the Botswana CTU.

Richard Hayes, DSc, FMedSci, is a professor of Epidemiology and International Health at the London School of Hygiene and Tropical Medicine in London, England.

Tonia Poteat, Ph.D., MPH, PA-C, is an assistant professor in the Department of Epidemiology at Johns Hopkins Bloomberg School of Public Health and a 2015-2016 HPTN Scholar. She completed her Ph.D. in International Health at Johns Hopkins University.