HIV Prevalence, Incidence, and HSV-2 Prevalence Among High-Risk MSM in Perú
What was HPTN 036?
A prospective cohort study with a six-month accrual period and 12 months of follow-up for enrolled HIV-uninfected participants, as well as a cross-sectional study of risk behaviors, partnership status, and HSV-2 serostatus of HIV-infected men who have sex with men.
Who participated in the study?
HIV-uninfected and HIV-infected men who have sex with men (MSM)
What happened during the study?
No treatment regimen, however STD and HIV pre-test, risk reduction, and post-test counseling were provided at each testing time point. In addition, participants were referred for STD treatment if need.
Study Documents
Study Details
To provide biomedical and behavioral data critical for the planning and implementation HPTN of HIV prevention trials in Lima, Perú.
(1) Prospective cohort study with a six-month accrual period and 12 months of follow-up for enrolled HIV-uninfected participants; (2) cross-sectional study of risk behaviors, partnership status, and HSV-2 serostatus of HIV-infected men who have sex with men.
HIV-uninfected and HIV-infected men who have sex with men (MSM)
500 HIV-uninfected MSM; 150-200 HIV-infected MSM
Accrual will require six months. HIV-uninfected participants will complete one year of follow-up. Therefore, the entire study should be completed within approximately 18 months.
None. However STD and HIV pre-test, risk reduction, and post-test counseling will be provided at each testing timepoint. In addition, participants will be referred for STD treatment if needed.
To determine prevalence, incidence, and risk factors for syphilis, HSV-2, and HIV among high-risk HIV-uninfected MSM.
Among HSV-2 seropositive men, evaluate informed consent procedures, eligibility criteria, and willingness to participate in a trial of daily suppressive acyclovir for HIV prevention.
To identify effective follow-up strategies for high-risk MSM in Lima to achieve at least 90% retention at 12 months.
To measure the use of condoms, barriers, and facilitators to enhance condom use with male and female partners.
To characterize the sexual networks of MSM, and the proportion of HIV-infected and HIV-negative men who are sexually active with both men and women.