About the HPTN

Mission Statement

The HPTN is dedicated to the discovery and development of new and innovative research strategies to reduce the acquisition and transmission of HIV.

The HIV Prevention Trials Network (HPTN) is a worldwide collaborative clinical trials network that brings together investigators, ethicists, community and other partners to develop and test the safety and efficacy of interventions designed to prevent the acquisition and transmission of HIV. HPTN studies evaluate new HIV prevention interventions and strategies in populations and geographical regions that bear a disproportionate burden of infection.

The HPTN research agenda is focused primarily on the use of integrated strategies: use of antiretroviral drugs (antiretroviral therapy and pre-exposure prophylaxis); interventions for substance abuse, particularly injection drug use; behavioral risk reduction interventions and structural interventions. The HPTN is committed to the highest ethical standards for its clinical trials and recognizes the importance of community engagement in all phases of the research process.

The HPTN was established in 2000, building on the work of the HIV Network for Prevention Trials (HIVNET). HPTN’s Leadership and Operations Center (LOC), is based at FHI 360, Durham, North Carolina. Its Laboratory Center (LC) is at Johns Hopkins University, Baltimore, Maryland and its Statistical and Data Management Center (SDMC) is housed within the Statistical Center for HIV/AIDS Research and Prevention (SCHARP) at the Fred Hutchinson Cancer Research Center in Seattle, Washington. The HPTN Modelling Centre, part of the SDMC, is a collaboration between the Department of Infectious Diseases Epidemiology at Imperial College London and SCHARP.

HPTN receives its funding from three NIH institutes: the National Institute of Allergy and Infectious Diseases, the National Institute of Mental Health and the National Institute on Drug Abuse.

Webinars

The HPTN Leadership and Operations Center (LOC)

The HPTN Statistical and Data Management Center (SDMC)


Conversations with the HPTN

Doreen Kemigisha, MPH, a member of the HPTN Community Working Group (CWG), is a senior health visitor, community educator, and qualitative coordinator at Makerere University – John Hopkins University (MU-JHU) Research Collaboration based at Mulago Hospital Complex in Kampala, Uganda. She has worked with MU-JHU since 2009, carrying out participant recruitment and retention activities for the HPTN and the Microbicide Trials Network.

Rona Siskind is a health specialist at the U.S. National Institute of Allergy and Infectious Diseases (NIAID) Division of AIDS (DAIDS) in Bethesda, Md., focusing on community engagement, training, and communications related primarily to HIV vaccine and prevention research. She has been at DAIDS for more than 30 years and has worked with all the HIV/AIDS clinical trials research networks. Since early in her tenure at DAIDS, she has worked with, and on behalf of, the networks’ community working groups and advisory boards.

Avelino (Jun) Loquere is the site coordinator for the ICAP at Columbia University Clinical Trials Unit (ICAP CTU) in New York. He has more than 20 years of experience in HIV care, treatment, and prevention research. Jun has experience working on multiple DAIDS-funded HIV clinical trials through the CPCRA, INSIGHT, ACTG, HVTN, and HPTN networks.

Jessica Yeager is a national and Texas state-certified peer recovery support specialist. She is currently a peer support services supervisor for HPTN 094. Jessica is an influential recovery community leader who thrives on innovative change to create purpose in our broken system, stomp out stigma, and help others heal while delivering the message of hope.